A series approx. 100 years ahead of TNG era, with transwarp and/or quantum slipstream an established, reliable drive tech.
Relations with the Romulan Star Empire has warmed to the point where they are sorta kinda like the Klingons in TNG...thus the Neutral Zone and the prohibition against cloaking tech have been abolished.
Phase Cloaks for Everybody
The commbadge has progressed to the point where it emits a virtual viewscreen allowing the wearer to talk face to face, or view data, etc.
Uses hologram tech with the same logic that allowed R2-D2 to image Leia's sides and rear, even though the droid only had a camera to photograph her front.
The Borg and the Dominion are now only nuicances that are dealt with occaisionally.
The new discovery to launch the show is The Worm...it makes wormholes.
This allows the UFP to explore neighboring galaxies...